COVID-19 Travel Information

Hampton Inn at Sikeston

Settle in for a relaxing stay at Sikeston's newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown and within walking distance to many shops and restaurants.

Settle in for a relaxing stay in one of our modern guest rooms. Enjoy the convenience of a mini-refrigerator, microwave, free Wi-Fi, coffeemaker, 42-inch flat-screen TV with premium cable channels and work desk with ergonomic chair. Upgrade to a studio suite for extra space and a separate seating area. 

Start each day with our free hot breakfast or, if you're in a hurry, grab one of Hampton's On the Run™ Breakfast Bags, available Monday through Friday. Stop by our Treats Shop any time of day or night for a quick snack or beverage. Stay in shape with a workout in our 24-hour fitness center or take a dip in our indoor heated pool. Plan a meeting in our 700 sq. ft. of meeting space fully equipped with A/V equipment.

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1240 Commerce Drive
Sikeston, MO 63801

Additional Information

Smoking Policy
No Smoking
Suitable For These Age Groups
All Ages
Activities Within 10 Miles
Historic District
Winery / Vineyard
Biking / Walking Trails
On-site Amenities
Breakfast Included
Fitness Center
Campsite Amenities
Indoor Pool
Room Amenities
Cable / Satellite TV
Wi-Fi (no Charge)