COVID-19 Travel Information

Enjoy a great night's rest and wake up to a hot, tasty breakfast when you stay at our Comfort Inn & SuitesĀ® hotel in Hannibal, Mo. Our affordable hotel is a great place to stay while exploring the many Mark Twain attractions Hannibal has to offer.

Amenities include:

Free Wi-Fi

Free hot breakfast

Meeting space

Fitness center

Indoor heated pool

Guest rooms feature:

Microwave and refrigerator

Premium bedding

Desk with ergonomic chair

Flat-screen TV

Coffee maker

Ideal for work-related travelers or those seeking a vacation hotel, you'll have easy access to other local attractions like:

Mark Twain Riverboat

Mark Twain Boyhood Home & Museum

Mark Twain Cave

Hannibal-LaGrange University

Hannibal Regional Hospital

Complete your plans for your northeast Missouri getaway by booking a guest room at our hotel near Mark Twain's Boyhood Home.


Daily   12:00AM — 12:00AM
4000 Market St.
Hannibal, MO 63401

Additional Information

Smoking Policy
No Smoking
Pet Policy
Pets Are Not Allowed
Guest Reservations Needed?
Reservations Recommended
On-site Amenities
Business Center
Fitness Center
Laundry Facilities
Campsite Amenities
Indoor Pool
RV / Bus Parking
Room Amenities
Cable / Satellite TV
Coffee Maker
Wi-Fi (no Charge)