Places to Stay

Comfort Inn & Suites – Hannibal

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Enjoy a great night’s rest and wake up to a hot, tasty breakfast when you stay at our Comfort Inn & Suites® hotel in Hannibal, Mo. Our affordable hotel is a great place to stay while exploring the many Mark Twain attractions Hannibal has to offer.

Amenities include:

Free Wi-Fi

Free hot breakfast

Meeting space

Fitness center

Indoor heated pool

Guest rooms feature:

Microwave and refrigerator

Premium bedding

Desk with ergonomic chair

Flat-screen TV

Coffee maker

Ideal for work-related travelers or those seeking a vacation hotel, you’ll have easy access to other local attractions like:

Mark Twain Riverboat

Mark Twain Boyhood Home & Museum

Mark Twain Cave

Hannibal-LaGrange University

Hannibal Regional Hospital

Complete your plans for your northeast Missouri getaway by booking a guest room at our hotel near Mark Twain’s Boyhood Home.


Daily   12:00 am — 12:00 am
4000 Market St.
Hannibal, MO 63401

Additional Information

Smoking Policy
No Smoking
Guest Reservations Needed?
Reservations Recommended
Pet Policy
Pets Are Not Allowed
On-site Amenities
Business Center
Fitness Center
Indoor Pool
Laundry Facilities
RV / Bus Parking
Hot Breakfast
Room Amenities
Cable / Satellite TV
Coffee Maker
Wi-Fi (no Charge)
Room Rates
Low Rate (per Day) $85
High Rate (per Day) $110