Route Du Vin Wine Trail

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Set amid the rolling hills along the Mississippi River in Southeast Missouri, the Route Du Vin wine trail beckons with award-winning wines, scenic views and communities filled with history. Enjoy restaurants, lodging, boutique shops and art galleries, located primarily in Farmington and Ste. Genevieve – the oldest European settlement in the state. The trail features six wineries, each with its own distinct character.


A. Cave Vineyard Winery & Distillery

Sample the wine and stop by the Biscotti Bar, featuring homemade biscotti in more than a dozen flavors. Take a stroll to the cave, located under the tasting room, where you can enjoy a picnic lunch.

B. Charleville Vineyard and Microbrewery

Try the wine and handcrafted beer in a rustic setting off the beaten path. Stay in an 1860s log cabin that has been refurbished and furnished with primitive antiques.

C. Chaumette Vineyards and Winery

Take in expansive views of the countryside while savoring the wine and dining inside or alfresco at the restaurant. The winery offers luxury villas, a fitness center and private cabanas by the pool.

D. Route Du Vin Wine Trail

Have a picnic and enjoy vintages made by a fourth generation winemaking family under the grape arbor at the winery located in a circa 1900 house in downtown Ste. Genevieve.

E. Sand Creek Vineyard

Pair your wine with pizza, sausage, cheese and chocolate in the tasting room, which features a large stone bar and cupola, or outside on the veranda.

F. Twin Oaks Vineyard and Winery

Travel to the middle of the vineyard to enjoy wine, premium beer and cocktails in the tasting room, covered porch or glass house.


A. Hotel Audubon, Grill and Bar

Located in Ste. Genevieve's historic downtown district, the restaurant has a wide-ranging menu featuring steak, seafood, pasta, sandwiches, local beers, wine and hand-crafted cocktails.

B. 12 West Bar and Grill

The upscale bar and grill on the square in Farmington serves steaks, chicken and seafood as well as specialty burgers, sandwiches, fish tacos, craft beer, wine and cocktails.

C. Grapevine Grill

Providing a farm-to-fork culinary experience using fresh, local ingredients, the restaurant at Chaumette Vineyard and Winery offers fine dining with Cajun, Creole and Southwest influences. A Cajun specialty is featured every Thursday evening.


A. The Villages at Chaumette Vineyards & Winery

Luxury lodging located at Chaumette Vineyards and Winery provides panoramic views in the heart of wine country. Seven villa suites offer kitchenettes, and 12 villas feature fully-equipped kitchens and fireplaces. Two dog-friendly villas are available for pet lovers.

B. Route Du Vin Wine Trail

Nine guest rooms are furnished with Victorian antiques and old-fashioned claw foot tubs. The hotel, built in the 1790s in Ste. Genevieve, includes a parlor, spacious dining room and game room for guests to enjoy.

C. Hotel Audubon, Grill and Bar

Nestled in Ste. Genevieve's historic district, the 1904 hotel blends old world charm with modern amenities. The seven rooms are named after birds – fitting for a hotel named for John James Audubon, the famous French American ornithologist, naturalist and painter who lived in Ste. Genevieve for several years.


A. Felix Valle House State Historic Site

Explore the area’s early history and some of the finest examples of rare French colonial architecture in the country, including the 1818 Federal style Felix Valle House, the vertical-log 1792 Amoureux House and the 1819 Shaw House.

B. Hawn State Park

Located between Ste. Genevieve and Farmington, the park is known for its towering pine trees, wild azaleas and rock formations. Its offers picnic sites, a shelter house, a campground, hiking and birding trails and a 10-mile backpacking trail.

C. Pickle Springs Natural Area

Hiking and bird watching are popular at this state conservation area. The two-mile Trail Through Time takes you past sandstone cliffs, canyons, arches, granite outcroppings and waterfalls.

D. Crown Ridge Tiger Sanctuary

Tour the non-profit big cat rescue working to provide a lifelong home to tigers who have been held in captivity and been abused or neglected or were no longer wanted.