A. Rosemary Berkel and Harry L. Crisp II Museum
Located in Cape Girardeau, this museum features the Crossroads Gallery, which includes exhibits and interactive kiosks highlighting the history of southeast Missouri, including: The Land and Waters; First Voices; First Peoples; Frontiers and Empires; River and Rail; North and South; Subsistence to Agribusiness; Expressions of Faith; and Change through Education.
B. Cape Girardeau Common Pleas Courthouse
On of the most historic sites in Cape, Common Pleas Courthouse was completed in 1854. It played a big part in the city's history, from Indian council meetings to the Civil War. On the west side of the courthouse stand three memorials: A cast of a Union soldier, who sits atop a fountain way, was presented by the Women's Relief Corps in 1911; another, made from Georgia silver gray marble, was presented to the city in 1931 by the United Daughters of the Confederacy; the third is a Vietnam Memorial. This attraction has an audio tour that you can dial into with your cell phone (while on-site).
C. Sikeston Depot Museum & Gallery
Located in 1916 train depot, in downtown Sikeston, this museum recounts the most important aspects of the area's culture. It includes an art gallery in which local artists display their work; and a cultural center displaying traveling exhibits from national museums.