The Clarksville Community Chamber of Commerce is organized for the purpose of advancing the economic, industrial, professional, cultural and civic welfare of the Clarksville area and thereby promoting the welfare of all area citizens. Clarksville, MO is located on Missouri Route 79 which is part of the Great River Road and is one of the most scenic highways along the Mississippi River. It overlooks U.S. Lock and Dam 24, providing a close vantage point to view all river boat and barge traffic. Clarksville is also one of the largest winter migrating areas for the bald eagle. A fabulous site for a wedding, Clarksville has restaurants, event halls, B&Bs, outdoor sites: whatever you would need for your special day. Eagle Days is the second weekend of January. An official Chili Cook-off event in the Riverfront Park is held on Saturday of the first full weekend in June. Clarksville’s oldest event is Applefest with parade and vendors and handmade crafts booths the second weekend of October.