Use this official website to find all things related to The Hill neighborhood in St. Louis. The Hill is known for its Italian heritage, famous world-class Italian restaurants, and Italian grocery stores.The Hill is on the south side of I-44, at exit 287; just west of the Missouri Botanical Garden. The official boundaries of the area are Manchester Avenue on the north, Columbia and Southwest Avenues on the south, South Kingshighway Boulevard on the east, and Hampton Avenue on the west.Note: The address shown is for St. Ambrose Catholic Church, located near the center of the district.